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. Author manuscript; available in PMC: 2019 Mar 24.
Published in final edited form as: Lancet. 2018 Mar 15;391(10126):1186–1196. doi: 10.1016/S0140-6736(18)30485-9

Figure 4. Changes in naive CD8 T cell and memory CD8 T cells populations.

Figure 4

Changes in expansion of naive CD8 T cells (A) and changes in memory CD8 T cells (B), as shown in fresh cells. Changes in the proportion of naive and memory CD8 T cells at each visit were assessed by two-tailed unpaired t tests relative to matched healthy controls at each timepoint and two-tailed paired t tests relative to visit 1. Error bars show SD. The number of patients (and healthy controls) contributing data differed at each visit. *p<0·01 relative to healthy matched control.

†p<0·05 relative to visit 1. ‡p<0·05 relative to healthy matched control. §p<0·001 relative to healthy matched control.