Figure 3.

Overexpression of cell cycle‐related and expression‐elevated protein in tumor (CREPT) promotes migration and invasion in Calu‐1 non‐small‐cell lung cancer cells. A, Representative images of wound healing assay for CREPT overexpressed Calu‐1 cells 12 hours and 24 hours after treatment. B, Statistical analysis indicates the overexpression of CREPT in Calu‐1 cells could significantly increase cell motility (P = .029). C, Representative images of Transwell migration assay for CREPT‐overexpressing Calu‐1 cells. D, Statistical analysis of the number of invasion cells between CREPT‐ overexpressing Calu‐1 cells and the control group (P = .039). E Representative images of Transwell invasion assay for CREPT‐overexpressing Calu‐1 cells and control cells. (F) Statistical analysis of the number of invasion cells between CREPT‐overexpressing Calu‐1 cells and the control group (P = .043). *P < .05