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. 2018 Feb 20;109(4):1263–1275. doi: 10.1111/cas.13515

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© 2018 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(A) Expression of SNCA in Group 4 medulloblastomas on the RNA level was significantly higher than each of the other three subgroups (P < .0001). (B) Significant difference was found in the proportions of α‐synuclein (α‐syn) immunoreactivity in Group 4 compared with WNT and SHH groups. *P < .05. Protein expression level in Group 4 (means, 27.62% ± 5.932%; n = 21) was higher than that of Group 3 (means, 19.44% ± 6.641%; n = 18), although no statistical significance was identified (P = .3632). (C) Expression of SNCA on RNA from NanoString assay and protein levels from immunohistochemistry staining showed significant correlation (P < .0001, R ² = .3256)