Figure 1.

Aberrant expression of BC005927 long, non‐coding RNA (lncRNA) in hypoxia‐induced gastric cancer (GC) cells and GC tissues. A, lncRNA‐BC005927 is upregulated under hypoxic culture conditions (1% O₂, 5% CO ₂, 94% N₂) in (A1) SGC7901 cells, (A2) MKN45 cells and (A3) MKN28 cells. B1, B2, C1, C2, lncRNA‐BC005927 expression was assessed by real‐time PCR in 95 pairs of human GC and adjacent tissues. β‐Actin was used as an internal control. Significant differences between samples were analyzed using the Wilcoxon signed‐rank test (P = .002, n = 95). (D) Kaplan ‐Meier's analysis of the correlation between BC005927 expression and overall survival (OS) of GC patients. In all panels, results are representative of at least 3 independent experiments *P < .05, **P < .01