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. 2018 Mar 5;109(4):988–1000. doi: 10.1111/cas.13519

Figure 4.

Figure 4

BC005927 promotes the metastasis and invasion of gastric cancer (GC) cells in vivo. SGC7901 cells transfected with BC005927‐si1, BC005927‐si2 or a negative control, MKN28 cells transfected with the LV‐BC005927‐expression vector or the control vector were injected into nude mice by the tail vein for an in vivo metastasis assay. Animals were killed 6 weeks after injection. A, Incidence of lung and liver metastasis in each group of nude mice. B1, Number of metastatic lung foci observed in each group. B2, Number of metastatic liver foci observed in each group. C1, Images showing representative hematoxylin and eosin (HE) staining of lung tissue samples from the different experimental groups. C2, Images showing representative HE staining of liver tissue samples from the different experimental groups. In all panels, the results are representative of at least 3 independent experiments