Figure 3.
Inhibitory effects of anlotinib on cell proliferation. A, Inhibitory effect of anlotinib on vascular endothelial growth factor (VEGF)‐ or FBS‐stimulated HUVEC proliferation. HUVEC were incubated with different concentrations of drugs together with FBS (20%) or VEGF (20 ng/mL). B, Effects of anlotinib on tumor cell proliferation. Tumor cells were cultured with 10% FBS and then treated with anlotinib. Cell viability was determined by sulforhodamine B (SRB) assay. IC 50 values are presented as means ± SD of 3 independent experiments