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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Bioorg Med Chem. 2018 Mar 15;26(8):1939–1949. doi: 10.1016/j.bmc.2018.02.040

Table 4.

18F to 125I uptake ratios obtained from the biodistribution of [18F]RL-II-2Rs15d/[125I]SGMIB-2Rs15d in SKOV-3 model in the current study compared with the same ratios obtained from the data for [18F]RL-I-2Rs15d/[125I]SGMIB-2Rs15d in BT474M1 model reported (Zhou et al., 2017).

18F/125I Ratio
Tissues 1 h
2 h
RL-I RL-II RL-I RL-II
Liver 10.82 ± 1.87 6.21 ± 1.60 12.15 ± 1.42 4.49 ± 0.26
Spleen 5.18 ± 1.46 4.05 ± 1.00 4.92 ± 0.82 3.11 ± 0.57
Lungs 5.02 ± 0.53 2.49 ± 0.55 4.87 ± 0.80 3.09 ± 0.51
Heart 2.31 ± 0.36 3.91 ± 1.58 2.12 ± 0.74 3.18 ± 0.46
Kidneys 1.19 ± 0.11 3.06 ± 0.29 0.88 ± 0.02 3.28 ± 0.43
Stomach 1.67 ± 0.27 1.60 ± 0.34 1.64 ± 0.15 0.42 ± 0.12
Muscle 1.39 ± 0.22 2.07 ± 0.76 1.23 ± 0.35 4.25 ± 1.77
Blood 1.59 ± 0.19 3.18 ± 1.11 2.07 ± 0.28 1.77 ± 0.30
Bone 1.83 ± 0.36 6.05 ± 3.33 2.18 ± 1.15 14.90 ± 6.53
Brain 1.71 ± 0.73 7.88 ± 5.01 1.22 ± 0.18 11.56 ± 4.57
Tumor 0.84 ± 0.03 1.16 ± 0.11 0.80 ± 0.02 1.35 ± 0.04