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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Bioorg Med Chem. 2018 Feb 10;26(8):1547–1559. doi: 10.1016/j.bmc.2018.01.032

Figure 5.

Figure 5

Effects of aromatic nitration on nitrite production. Data extrapolated from Table 1 and presented as the mean % change of nitrite activity relative to the control, (a) The compounds listed in each pairing differ only by the presence/absence of a nitro group in the isoindolinone 4-position. Hydro versions appear on the left, while nitro analogs appear on the right, (b) Comparison of 4-position substituent effects.