Table 3.

Anti-angiogenesis properties of substituted phthalimidines.

compound	structure	% nitritea	vessel lengthb	# of vesselsc
11		101	105.1±4.9	19.5±0.5
21		72	42.1±3.3	14.0±1.4
9		50	83.1±2.4	18.2±0.4
22		49	42.8±9.2	8.6±2.7
24		11.5	86.4±2.8	22.0±0.5
20		9.2	48.2±1.9d	14.6±0.6d

^anitrite data extrapolated from Table 1; presented as mean % of control

^bvessel length in µm, obtained at 10µg/mL; presented as mean ± S.E.M

^cvessel number obtained at 10µg/mL; values presented as mean ± S.E.M

^dcompound 20 screened at 5µg/mL; values presented as mean ± S.E.M