Table 3.
OR | 95% CI | p-value | |
---|---|---|---|
Patient satisfaction with pre-test genetic counselling (model 1) | |||
Type of genetic test | |||
APC test a | 7.13a | 1.08 - infa | 0.039a |
BRCA1/2 tests | 6.00 | 1.19–30.36 | 0.030 |
Thrombophilia tests (reference) | 1.00 | – | – |
Carrier status (reference = non-carrier) | 0.44 | 0.11–1.81 | 0.254 |
Patient satisfaction with post-test genetic counselling (model 2) | |||
Type of genetic testing | |||
APC test | 18.97 | 2.46–146.36 | 0.005 |
BRCA1/2 tests | 32.44 | 7.07–148.88 | <0.001 |
Thrombophilia tests (reference) | 1.00 | – | – |
Carrier status (reference = non-carrier) | 1.03 | 0.41–2.58 | 0.948 |
Patient experience of collaboration between caregivers (model 3) | |||
Type of genetic test | |||
APC test | 0.28 | 0.08–1.08 | 0.064 |
BRCA1/2 tests | 0.49 | 0.17–1.37 | 0.174 |
Thrombophilia tests (reference) | 1.00 | – | – |
Carrier status (reference = non-carrier) | 1.08 | 0.52–2.26 | 0.830 |
Type of health professional referring patient for test | |||
Geneticist | 0.43 | 0.11–1.71 | 0.232 |
Specialist | 0.22 | 0.07–0.77 | 0.017 |
Primary care physician (reference) | 1.00 | – | – |
Post-test genetic counselling | |||
Yes, by a geneticist | 2.20 | 0.83–5.85 | 0.113 |
Yes, by a specialist | 0.55 | 0.19–1.58 | 0.269 |
Yes, by both a geneticist and a specialist | 8.53 | 2.75–26.43 | <0.001 |
No (reference) | 1.00 | – | – |
Familiarity (reference = no) | 2.39 | 1.02–5.60 | 0.045 |
Self-perceived improvement in life quality (model 4) | |||
Type of genetic test | |||
APC test | 2.97 | 1.14–7.72 | 0.025 |
BRCA1/2 tests | 1.41 | 0.74–2.69 | 0.294 |
Thrombophilia tests (reference) | 1.00 | – | – |
Carrier status (reference = non-carrier) | 0.52 | 0.28–0.97 | 0.040 |
Gender (reference = male) | 1.78 | 0.91–3.47 | 0.088 |
a Exact logistic regression was used because of convergence failure, median unbiased estimate, 95% CI and exact p-value were reported for dummy APC testing [14].