Table 1.

Table showing treatments (genetic or pharmacological) used by different authors as potential therapies for SCI and that have been shown to reduce FasL/Fas signaling and/or caspase-8 activation in animal models.

In the “Molecular effect” column the arrows indicate a decreased expression of the corresponding molecule/s. The type of injury and the behavioral tests used to reveal behavioral improvements are also indicated in the table. Treatments that have been translated to the clinic or that are in clinical trials are highlighted in gray. Abbreviations: BBB, Basso, Beattie, Bresnahan score; BMS, Basso mouse scale score; MDI, motor deficit index score.