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. 2018 Apr 3;12:62. doi: 10.3389/fnbeh.2018.00062

Figure 1.

Figure 1

Behavioral performances of mice repeatedly exposed to elevated plus maze (EPM) tests. (A) An overview of the maze. (B) A mouse was subjected to EPM tests for five consecutive days. One recording day was composed of two 5-min sessions (1st and 2nd sessions) with an intersession interval of 10 min. (C) Histological confirmation of a recording site in the prefrontal cortex (PFC) and dorsal hippocampal CA1 (HPC) areas in a cresyl-stained section. The arrowheads indicate the electrode tracks. (D) Schematic illustration of the recording configuration from a freely moving mouse. (E) Representative electrophysiological recordings of local field potential (LFP) signals from the PFC and HPC, an electrocardiogram (ECG) signal, an electromyogram (EMG) signal from the dorsal neck muscle, and a Resp signal from the olfactory bulb. (F–H) Average percentage of time spent in open arms, number of entries into open arms, and running speed in the maze. Each gray dot represents one mouse. The statistical results in these figures are described in the main text.