Figure 2.

Peripheral physiological signals during the EPM test. (A) Representative animal’s running speed, root mean square (RMS) of an EMG signal, heart rates and color-coded power spectrum of a respiratory signal with the frequency giving the maximum power indicated by the cyan line. Periods when the animal was located in open and closed arms and the center are represented in magenta, green and black lines, respectively. (B–D) Color-coded animal’s trajectory shown by dots. The color codes represent the RMS of EMG signals (B), heart rates (C) and respiratory rates (D) corresponding with an individual animal’s locations. (E–G) Average RMS of EMG signals, heart rates and respiratory rates plotted for open and closed arms in individual sessions. The statistical results in these figures are described in the main text.