Fig 2.
Relaxation response of arterioles to bradykinin before cardioplegia arrest and cardiopulmonary bypass (pre-CP/CPB) with (squares) and without (circles) the selective cyclooxygenase (COX)-2 inhibitor NS398 from (A) no diabetes mellitus (ND) patients, (C) controlled diabetes (CDM) patients, and (E) uncontrolled diabetes (UDM) patients. The relaxation response of post-CP/CPB arterioles to bradykinin with (squares) and without (circles) the selective COX-2 inhibitor NS398 from (B) ND, (D) CDM, and (F) UDM patients. Data are mean ± standard error of the mean; n = 6 per group. *p < 0.05 versus bradykinin alone. **p < 0.001 versus bradykinin alone.