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. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Mod Pathol. 2016 Feb 19;29(5):500–510. doi: 10.1038/modpathol.2016.36

Fig. 2.

Fig. 2

Partial GTG-banded karyotype, metaphase and interphase FISH of Case 1. Partial karyotype (top) shows a chromosome 12, del(12), chromosome 14 and der(14). In the metaphase FISH (middle), absence of hybridization of both HMGA2 probes (5′ green and 3′ orange) is observed on the del(12) whereas amplification of the 3′ HMGA2 (orange) is detected on the der(14). In the interphase FISH (bottom) the absence of 3′ HMGA2 signal (green, 5′ HMGA2 not performed) is observed and its amplification is detected on the der(14) next to the 14q24 signal (orange).