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. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Mod Pathol. 2016 Feb 19;29(5):500–510. doi: 10.1038/modpathol.2016.36

Table 1.

GTG-banded karyotype and metaphase FISH characterization of intravenous leiomyomatosis cases

Case No. Karyotype Metaphase FISH interpretation
1 45,XX,del(12)(q?14q?15),hsr(14)(q2?1),-22[7].ish
del(12)(q14.3q14.3)(5′HMGA2-,3′HMGA2-),hsr(14)amp(3′HMGA2)		 HMGA2 amplification on abnormal 14q, breakpoint 5′ (centromeric) to 3′HMGA2
21 45,XX,der(14)t(12;14)(q15;q24),-22.ish
der(14)t(12;14) (RAD51L1+,5′HMGA2+,3′HMGA2+)		 3 copies of HMGA2, breakpoint 5′ (centromeric) to HMGA2
32 45,XX,-10,add(11)(q11),der(14)t(12;14)(q15;q24)[12]/45,XX,-10,add(11)(q11),t(12;14)(q15;q24)[3].ish
der(14)t(12;14)(5′HMGA2+,3′HMGA2+)/t(12;14)(5′HMGA2-,3′HMGA2-;5′HMGA2+,3′HMGA2+)		 Mosaic karyotype with 3 and 2 copies of HMGA2, breakpoint 5′ (centromeric) to HMGA2
1

Previously published as ST00-142 (19)

2

Previously published as ST02-0165 (18)