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. 2018 Apr 9;25:33. doi: 10.1186/s12929-018-0433-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — a Experimental B-cell and CD4+ Т-cell epitopes, homologous to the consensus НА2 (76–130) fragment by more than 90%. IEDB database search result is presented; non homologous amino acids are marked with red. Green font identifies the single B-cell epitope. Black font identifies the CD4+ T-cells epitopes b Potential CD8+ Т-cell epitopes inside HA2(76–130) fragment for a representative set of alleles; results of analysis using NetCTLpan1.1 Server is shown. Blue font identifies the CD8+ T-cells epitopes