Table 4.
Hemodynamic parameters. All the groups were statistically compared by ANOVA followed by Tukey’s multiple comparison
| Parameters | Control | Crocin | COPD | COPD + Crocin |
|---|---|---|---|---|
| LVDP (mmHg) | 79.66 ± 7.31 | 83.61 ± 6.56 | 86.82 ± 3.74 | 82.37 ± 6.60 |
| LVEDP (mmHg) | 7.58 ± 0.46 | 7.63 ± 0.36 | 8.03 ± 0.25 | 7.75 ± 0.35 |
| LVSP (mmHg) | 87.25 ± 7.28 | 91.25 ± 6.67 | 95.37 ± 4.17 | 89 ± 5.78 |
| dp/dt max (mmHg) | 2864.25 ± 141.54 | 2934.25 ± 71.22 | 3078.87 ± 93.48* | 2900.75 ± 144.72† |
| dp/dt min (mmHg) | − 2987.87 ± 147.05 | − 3016 ± 118.03 | − 3052.25 ± 84.74 | − 3011.50 ± 92.42 |
| RPP (mmHg/min) | 22,195.12 ± 3120 | 24,103.75 ± 3201 | 27,518.75 ± 1227** | 23,406.06 ± 3351† |
| Perfusion pressure (mmHg) | 63.25 ± 5.11 | 64 ± 4.44 | 59.12 ± 6.46 | 61 ± 7.92 |
| HR (bpm) | 259 ± 16.93 | 263 ± 18.49 | 280 ± 21.61* | 262 ± 21.76† |
*P < 0.05 and **P < 0.01 vs. Control, †P < 0.05 vs. COPD. Data are expressed as the mean + SEM, n = 8