Table 1.

Gene expression studies of LMTK2 in neurodegeneration

Disease	Research model	Disease sample	Control sample	LMTK2 gene expression in disease sample	Statistical significance	Reference
Alzheimer’s disease	Mouse tissue	Tau P301L cortex and hippocampus	Wild-type cortex and hippocampus	Decreased	Not known	[54]
Parkinson’s disease	Human tissue	Substantia nigra	Substantia nigra from controls	Decreased	Not known	[107]
Amyotrophic lateral sclerosis	Human embryonic stem cell-derived motor neuron	Neurons exposed to mutant SOD1 astrocyte conditioned medium	Non-treated neurons	Decreased	Not known	[108]
Huntington’s disease	Mouse tissue	DE5 (D9-N171-98Q) striatum	Wild-type striatum	Decreased	Yes (p = 0,025)	[109]