Table 3.
Stratification analysis of lncRNA MALAT1 polymorphisms and clinical features of CAD
| Genotypes | TCH (mmol/L) | TG (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | ||||
|---|---|---|---|---|---|---|---|---|
| Mean ± SD | P value | Mean ± SD | P value | Mean ± SD | P value | Mean ± SD | P value | |
| rs11227209 | ||||||||
| CC | 4.95 ± 0.74 | 1.95 ± 1.07 | 1.33 ± 0.36 | 2.69 ± 0.67 | ||||
| CG/GG | 4.72 ± 0.86 | 0.02 | 1.95 ± 1.02 | 0.94 | 1.34 ± 0.40 | 0.86 | 2.82 ± 0.80 | 0.13 |
| rs619586 | ||||||||
| AA | 4.94 ± 0.77 | 1.98 ± 1.07 | 1.32 ± 0.36 | 2.69 ± 0.68 | ||||
| AG/GG | 4.76 ± 0.79 | 0.04 | 1.85 ± 1.01 | 0.27 | 1.37 ± 0.41 | 0.25 | 2.81 ± 0.77 | 0.11 |
| rs664589 | ||||||||
| CC | 4.93 ± 0.74 | 1.97 ± 1.08 | 1.32 ± 0.36 | 2.71 ± 0.70 | ||||
| CG/GG | 4.84 ± 0.85 | 0.28 | 1.92 ± 1.00 | 0.67 | 1.36 ± 0.39 | 0.21 | 2.72 ± 0.71 | 0.87 |
| rs3200401 | ||||||||
| CC | 4.95 ± 0.75 | 1.98 ± 1.05 | 1.33 ± 0.36 | 2.70 ± 0.69 | ||||
| CT/TT | 4.77 ± 0.81 | 0.02 | 1.87 ± 1.07 | 0.29 | 1.35 ± 0.39 | 0.61 | 2.74 ± 0.72 | 0.58 |
CAD coronary atherosclerotic heart disease, TCH total cholesterol, SD standard deviation, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol