Table 4.
Differentially expressed genes between subjects in the highest and lowest plasma n-3 tertile
| Gene | Highest tertile (n 18) | Lowest tertile (n 18) | Mean Difference | P |
|---|---|---|---|---|
| SNX5 | 8.53 ± 0.13 | 8.43 ± 0.14 | 0.10 | 0.029 |
| AMPD3 | 6.94 ± 0.06 | 6.88 ± 0.06 | 0.06 | 0.012 |
| LCAT | 6.93 ± 0.07 | 6.99 ± 0.07 | − 0.06 | 0.013 |
| RORA | 7.11 ± 0.13 | 7.21 ± 0.10 | − 0.10 | 0.018 |
| FAM13A | 7.33 ± 0.14 | 7.43 ± 0.15 | − 0.10 | 0.049 |
| UBE2L3* | 7.16 ± 0.16 | 7.28 ± 0.17 | − 0.12 | 0.035 |
| ANKRA2 | 9.10 ± 0.20 | 9.25 ± 0.17 | − 0.15 | 0.017 |
| THBS1 | 7.29 ± 0.32 | 7.62 ± 0.43 | − 0.32 | 0.016 |
Expression of genes is given as mRNA level. Values are presented as mean ± SD and are log2 transformed. Differences between tertiles were analyzed using the independent samples t test. P values < 0.05 were considered significant
*Genes differentially expressed between subjects in the highest and lowest n-3 tertile and between subjects in the highest and lowest SFA to PUFA ratio tertile. The genes presented in italics are expressed by more than one probe (shown in Additional file 3: Table S3). The probe with lowest p-value is shown in Table 4