Fig. 4.

SYK regulates tumor formation. (A) Representative image and colony size quantification of BS287 cells either mock-treated or treated with BAY for 5 days. (B) Flow cytometric analysis of side population and quantification of BS287 cells either mock-treated or treated with BAY for 5 days. (C) Images and sizes of tumors of mock- or BAY-treated BS287 cells injected into nude mice at a threshold size of 1 cm³. (D) Tumor take rates of LN229 empty vector control containing the human influenza hemagglutinin (HA) tag or wild-type SYK tumors in nude and BNX mice. (E) Organ sizes of tumor-positive mice implanted with LN229 empty vector control or wild-type SYK tumors.