Table 4.
Association of diabetes with Braak-Braak and CERAD scores, considering interaction terms of diabetes with race and Apolipoprotein E allele ε4 (n = 1,037)
Braak-Braak Score OR (95%CI) |
P* | CERAD Score‡ OR (95%CI) |
P* | |
---|---|---|---|---|
Interaction between diabetes and race | ||||
White | 1.06 (0.71–1.58) | 0.85 | 0.93 (0.60–1.44) | 0.76 |
Black+Brown | 1.14 (0.68–1.90) | 1.07 (0.60–1.90) | ||
Interaction between diabetes and APOE ε4§ | ||||
Absence of APOE ε4 | 0.76 (0.41–1.38) | 0.01 | 0.75 (0.38–1.50) | 0.12 |
Presence of APOE ε4 | 2.82 (1.28–6.23) | 1.79 (0.78–4.11) |
p-value for the interaction term. Multivariable ordinal logistic regression adjusted for age, sex, race, education, hypertension, dyslipidemia, physical inactivity, smoking, and alcohol use.
CERAD, Consortium to Establish a Registry for Alzheimer’s Disease.
Data available for 524 participants.