Table 1.
Study (ref.) | Year | OS biomarker | Patients | Results |
---|---|---|---|---|
Similar OS status in HD and PD (6 studies) | ||||
Filiopoulos et al. [42] | 2009 | Serum TAC Serum SOD |
20 HD 11 PD |
Similar in HD and PD |
Ahmadpoor et al. [43] | 2009 | Serum GPx activity Serum TAC Serum GSH RBC GSH |
30 HD 12 CAPD |
Similar in HD and CAPD |
Mekki et al. [44] | 2010 | Serum TBARS Serum SOD Serum GPx Serum CAT |
20 HD 20 PD |
Similar in HD and PD |
Castoldi et al. [41] | 2010 | Serum 8-OHdG Serum ox-LDL |
51 HD 17 PD |
Similar in HD and PD |
Samouilidou et al. [40] | 2012 | Serum ox-LDL | 31 HD 24 PD |
Similar in HD and PD |
Mehmetoglu et al. [45] | 2012 | Serum TAC Serum coenzyme Q10 |
38 HD 41 CAPD |
Similar in HD and CAPD |
| ||||
Lower OS status in HD than in PD (3 studies) | ||||
Taylor et al. [47] | 1992 | Serum MDA | 20 HD 18 CAPD |
Higher in CAPD versus HD |
Serum SOD | Similar in CAPD and HD | |||
McGrath et al. [48] | 1995 | Serum MDA | 20 HD 20 CAPD |
Higher in CAPD versus HD |
Al-Hweish et al. [46] | 2010 | Serum MPO | 56 HD 28 CAPD |
Higher in CAPD versus HD |
| ||||
Higher OS status in HD than PD (24 studies) | ||||
Pastor et al. [72] | 1993 | Serum AT levels (antioxidant) | 18 HD 14 CAPD |
Lower in HD versus CAPD |
Ross et al. [68] | 1997 | Serum cysteine | 20 HD 20 PD |
Higher in HD versus PD |
Serum glutathione | Similar in HD and PD | |||
Zima et al. [71] | 1998 | Serum. RBC and whole blood Zn, Cu, and Se (antioxidants) | 36 HD 18 CAPD |
Lower in HD versus CAPD |
Kielstein et al. [50] | 1999 | Serum ADMA | 43 HD 37 PD |
Higher in HD versus PD |
Takayama et al. [69] | 2001 | Serum glutathionyl hemoglobin | 30 HD 10 CAPD |
Higher in HD versus CAPD |
Donate et al. [66] | 2002 | Serum carbonyl proteins | 42 HD 21 PD |
Higher in HD versus PD |
Lim et al. [51] | 2002 | Serum F2-isoprostanes | 35 HD 30 CAPD |
Higher in HD versus CAPD |
Usberti et al. [54] | 2002 | Serum ROS, MDA, and TAC | 55 HD 16 PD |
Higher in HD versus PD |
Serum AT (antioxidant) | Lower in HD versus PD | |||
Yonova et al. [59] | 2004 | Serum MDA Serum ox-LDL |
22 HD 22 CAPD |
Higher in HD versus PD |
Serum vitamin E Serum vitamin C Serum GPx |
Lower in HD versus PD | |||
Lucchi et al. [53] | 2005 | RBC GSH | 23 HD 15 CAPD |
Higher in HD versus PD |
Sela et al. [55] | 2005 | Rate of superoxide release from activated neutrophils | 30 HD 30 CAPD |
Higher in HD versus CAPD |
Morimoto et al. [56] | 2005 | Serum ADMA | 31 HD 43 PD |
Higher in HD versus PD |
Pawlak et al. [57] | 2007 | Serum Cu/Zn SOD Serum VEGF |
25 HD 45 PD |
Higher in HD versus PD |
Mitrogianni et al. [65] | 2009 | Serum carbonyl proteins | 25 HD 21 PD |
Higher in HD versus PD |
De Rojas and Mateo [73] | 2009 | RBC SOD activity RBC CAT activity (antioxidants) |
16 HD 11 CAPD |
Lower in HD versus CAPD |
Kayabasi et al. [58] | 2010 | Serum MDA and GPx | 32 HD 39 CAPD |
Similar in HD versus CAPD |
Serum SOD (antioxidant) | Lower in HD versus CAPD | |||
Guoa et al. [60] | 2011 | Serum TBARS, carbonyl compounds | 20 HD 20 PD |
Higher in HD versus PD |
GPx and CAT activity (antioxidant markers) | Lower in HD versus PD | |||
Serum Zn, Se (antioxidants) | Lower in HD versus PD | |||
Zhou et al. [61] | 2012 | Serum AOPPs | 1539 HD 556 CAPD |
Higher in HD versus PD |
Marques de Mattos et al. [62] | 2012 | Serum AOPPs | 48 HD 20 CAPD |
Higher in HD versus PD |
Capusa et al. [64] | 2012 | Serum TBARS | 16 HD 17 CAPD |
Higher in HD versus PD |
Serum TAC (antioxidant marker) | Similar in HD and PD | |||
Puchades et al. [52] | 2013 | Serum carbonyl proteins Serum F2-isoprostanes Serum 8-OHdG |
30 HD 31 PD |
Higher in HD versus PD |
Serum GPx Serum GSH Serum CAT, SOD (antioxidants) |
Lower in HD versus PD | |||
Marques de Mattos et al. [63] | 2014 | Serum AOPPs Serum AGEs |
21 HD 19 PD |
Higher in HD versus PD |
Serum vitamin C+A+E (antioxidants) | Similar in HD and PD | |||
Xu et al. [67] | 2015 | Serum8-OHdG | 220 HD 83 PD |
Higher in HD versus PD |
Stępniewska et al. [70] | 2016 | Platelet CAT activity (antioxidant marker) | 37 HD 23 PD |
Lower in HD versus PD (0.82 in PD versus 0.52 before HD and 0.35 after HD) |
OS: oxidative stress; HD: hemodialysis; PD: peritoneal dialysis; ox-LDL: oxidized low-density lipoprotein; 8-OHdG: 8-hydroxy-2′-deoxyguanosine; TAC: total antioxidant capacity; SOD: superoxide dismutase; MPO: myeloperoxidase; CAPD: continuous ambulatory peritoneal dialysis; MDA: malondialdehyde; ADMA: asymmetric dimethylarginine; RBC: red blood cell; GSH: reduced glutathione; ROS: reactive oxygen species; AT: alpha-tocopherol; SOD: superoxide dismutase; VEGF: vascular endothelial growth factor; GPx: glutathione peroxidase; TBAR: thiobarbituric acid-reactive substances; AOPPs: advanced oxidation protein products; CAT: catalase; Zn; zinc; Cu; copper; Se: selenium.