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Activation of CAE-induced membrane receptor apoptosis pathway is related to the regulation of COX-2: the expression of COX-2 and EP2 was dependent on CAE concentrations, but all were lower than the control group. Data are expressed as mean ± SD (n = 3); #P < 0.05 versus CAE-50 ug/ml group, ##P < 0.01 versus CAE-50 ug/ml group; ∗P < 0.05 versus CAE-50 ug/ml group, ∗∗P < 0.01 versus CAE-50 ug/ml group.
