Skip to main content
. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Am J Psychiatry. 2016 Oct 24;174(3):256–265. doi: 10.1176/appi.ajp.2016.16060721

FIGURE 3. Association of NRG3 Class I–IV mRNA Expression With rs10748842 and rs6584400 Genotypes in Mood Disordersa.

FIGURE 3

aIndividual data points represent quantitative, normalized subject-level gene expression, with the horizontal line indicating the groups’ mean gene expression and whiskers indicating the standard deviation of the mean. Part A, TT genotype: bipolar disorder, N=22; depression, N=49. Part A, TC genotype: bipolar disorder, N=4; depression, N=10. Part B, TT genotype: bipolar disorder, N=25; depression, N=59. Part B, TC genotype: bipolar disorder, N=7; depression, N=10). Part C, GG genotype: bipolar disorder, N=19; depression, N=45. Part C, A-carrier genotype: bipolar disorder, N=6; depression, N=14. Part D, GG genotype: bipolar disorder, N=24; depression, N=53. Part D, A-carrier genotype: bipolar disorder, N=8; depression, N=16. Significant differences from the nonrisk group are indicated by asterisks.

*p<0.05. **p<0.01. ***p<0.001.