Figure 3. Expression of ILK, E-cadherin, ZEB and CD44 in metastatic CRC is associated with chemotherapy response. Immunohistochemical expression of ILK (A, B), E-cadherin (C, D), ZEB (E, F) and CD44 (G, H) is shown in representative cases of responders (left column) and nonresponders (right column). Non-responders to chemotherapy show higher expression of ILK (B), ZEB (F) and CD44 (H) and decreased expression of E-cadherin (D) compared to responders. Bars correspond to 50 μm.