Figure 6. Immunofluorescence analysis of EMT markers in HT29, 5-FUR cells and 5-FUR cells pre-treated with QLT0267 (5-FUR+QLT). Decreased expression of E-cadherin and increased expression of vimentin, Snail and ZEB can be seen in 5-FU resistant cells (5-FUR) compared to HT29 cells while treatment of resistant cells with QLT0267 (5-FUR+QLT) results in increased expression of E-cadherin and decreased expression of Vimentin, Snail and ZEB. Nuclei are stained with Hoechstain. Representative results of three independent experiments are shown.
