Table 3. P-values from pleiotropic meta-analysis of GRASP results for SNPs within ±1Mb flanking region of the index SNPs not reported in GRASP for 20 selected phenotypes (Table 1).
| Strongest LD | Smallest p-value | |||||||
| ID | Index SNP | Chr | Flanking SNP1 | LD | PGRASP | Flanking SNP2 | LD | PGRASP |
| 3 | rs16834550 | 1 | rs2377856 | 0.557 | 3.23E-01 | rs4949302 | 0.008 | 7.03E-06 |
| 12 | rs1969742 | 1 | rs2777987 | 1.000 | 3.27E-01 | rs7528684 | 0.089 | 3.43E-05 |
| 15 | rs1934628 | 1 | rs6665563 | 1.000 | 4.32E-01 | rs6540664 | 0.000 | 1.83E-05 |
| 27 | rs755503 | 2 | rs10186614 | 0.718 | 1.81E-01 | rs6730157 | 0.055 | 1.16E-18 |
| 37 | rs16829273 | 3 | rs6769314 | 0.772 | 1.82E-01 | rs9825140 | 0.000 | 5.91E-05 |
| 40 | rs10012631 | 4 | rs1814082 | 0.266 | 3.34E-01 | rs6831443 | 0.002 | 1.04E-03 |
| 44 | rs1460770 | 4 | rs11098258 | 0.745 | 4.14E-01 | rs17046113 | 0.000 | 5.26E-04 |
| 47 | rs259130 | 5 | rs259114 | 0.418 | 4.01E-01 | rs13157900 | 0.002 | 1.36E-19 |
| 48 | rs980831 | 5 | rs17160705 | 0.196 | 2.99E-01 | rs10037968 | 0.007 | 1.21E-04 |
| 55 | rs6936620 | 6 | rs6457702 | 0.796 | 4.09E-01 | rs9273363 | 0.001 | 1.52E-289 |
| 58 | rs9482188 | 6 | rs11750990 | 0.915 | 2.27E-01 | rs1015451 | 0.420 | 2.35E-24 |
| 60 | rs7785072 | 7 | rs12671830 | 0.322 | 4.31E-01 | rs864745 | 0.000 | 7.68E-12 |
| 63 | rs10953325 | 7 | rs734688 | 0.480 | 4.03E-01 | rs13245899 | 0.000 | 2.74E-22 |
| 64 | rs7807451 | 7 | rs10224905 | 0.276 | 3.78E-01 | rs3807989 | 0.004 | 5.85E-06 |
| 67 | rs700278 | 7 | rs696773 | 0.625 | 3.69E-01 | rs802196 | 0.108 | 1.84E-02 |
| 71 | rs7851478 | 9 | rs16937690 | 0.745 | 3.97E-01 | rs7022576 | 0.001 | 1.23E-05 |
| 73 | rs2987900 | 9 | rs1536859 | 0.879 | 4.34E-01 | rs3852402 | 0.025 | 2.50E-05 |
| 74 | rs4149313 | 9 | rs961160 | 0.005 | 7.40E-02 | rs960644 | 0.003 | 8.03E-03 |
| 76 | rs1476946 | 9 | rs2014343 | 0.824 | 3.40E-01 | rs7029898 | 0.000 | 1.14E-03 |
| 81 | rs2442100 | 11 | rs2084439 | 0.762 | 3.11E-01 | rs2517996 | 0.000 | 3.82E-03 |
| 82 | rs11045743 | 12 | rs4149012 | 0.633 | 1.45E-01 | rs7134375 | 0.046 | 9.02E-10 |
| 89 | rs670676 | 13 | rs682573 | 0.478 | 3.86E-01 | rs9943924 | 0.000 | 9.90E-06 |
| 90 | rs359412 | 13 | rs359357 | 0.968 | 2.54E-01 | rs275896 | 0.000 | 4.27E-03 |
| 91 | rs4903274 | 14 | rs11621041 | 0.807 | 3.89E-01 | rs12433610 | 0.009 | 8.04E-04 |
| 92 | rs4899173 | 14 | rs2127870 | 0.947 | 3.73E-01 | rs1256507 | 0.001 | 4.78E-04 |
| 93 | rs7151718 | 14 | rs10484104 | 1.000 | 4.07E-01 | rs1978243 | 0.001 | 1.18E-34 |
| 96 | rs626744 | 15 | rs16962739 | 0.155 | 4.09E-01 | rs3848128 | 0.000 | 1.68E-03 |
| 98 | rs12444489 | 16 | rs8052106 | 0.599 | 2.28E-01 | rs3764261 | 0.000 | 0.00E+00 |
| 100 | rs246134 | 16 | rs246141 | 0.807 | 4.27E-01 | rs9929218 | 0.000 | 1.54E-05 |
| 105 | rs11539879 | 17 | rs1046446 | 0.369 | 2.71E-02 | rs9892909 | 0.003 | 9.29E-06 |
| 114 | rs8136986 | 22 | rs16997937 | 0.355 | 1.59E-01 | rs5768709 | 0.000 | 1.68E-04 |
Chr = chromosome. LD: linkage disequilibrium, r2.
Strongest LD: SNPs with the strongest LD reported in GRASP within ±1Mb flanking region of the index SNPs.
Smallest p-value: SNPs from the ±1Mb flanking region of the index SNPs attained smallest p-values in our pleiotropic meta-analysis of results reported in GRASP.
PGRASP: p-values from the pleiotropic meta-analysis of the results for flanking SNPs reported in GRASP.