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. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Adv Immunol. 2016 Apr 5;131:1–59. doi: 10.1016/bs.ai.2016.02.001

Table 1.

Cellular and subcellular carriers of MDA epitopes.

Carrier type Induction Method of Detection References
Microvesicles (MV)
Circulating MV Flow cytometry (Tsiantoulas et al., 2015)
Platelet MV Ionomycin Flow cytometry (Tsiantoulas et al., 2015)
Endothelial MV tert-butyl hydroperoxide, Fe2+ Flow cytometry (Huber et al., 2002)
Monocytic MV Cholesterol Flow cytometry (Liu et al., 2012)
Activated or dying cells
Retinal pigment epithelial cells Heat Immunofluorescence (Weismann et al., 2011)
Thymocytes PMA Flow cytometry, Immunofluorescence (Chou et al., 2009)
Jurkat T cells UV Flow cytometry (Amir et al., 2012)
Endothelial cells Serum deprivation Flow cytometry, Immunofluorescence (Chang et al., 1999)
Thymocytes Dexamethasone Flow cytometry, Immunofluorescence (Chang et al., 1999)
Jurkat T cells UV Flow cytometry, Immunofluorescence (Tuominen et al., 2006)
THP-1 cells Cholesterol Immunofluorescence (Liu et al., 2012)
Erythrocytes Ageing HPLC (Gil et al., 2002)
Platelet Metabolic syndrome, sickle cell anemia Mass Spectrometry (Zagol-Ikapite et al., 2015)