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. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Nat Chem Biol. 2017 May 15;13(7):745–749. doi: 10.1038/nchembio.2375

Figure 3. Crystal structure of Etr1p WT and the T175V variant.

Figure 3

Overlay of crystal structures of Etr1p WT and the T175V variant, co-crystallized with NADP+ and soaked with crotonyl-CoA. The structures superimpose with a rmsd of 0.45 Å. The only notable difference near the active site is a slight shift in the nicotinamide ring of NADP+.