TABLE 1.
Day 18 ceramide mouse heart high-fat diet lipidomics (pM/mg)
| N-acyl chain | Control | Control + myriocin | Milk-fat diet | Milk-fat diet + myriocin |
|---|---|---|---|---|
| Total | 104.7 ± 24.0 | 134.8 ± 23.8 | 191.2* ± 21.9 | 128.5 ± 16.3 |
| C14 | 0.2 ± 0.1 | 0.4 ± 0.1 | 1.5 ± 0.7 | 1.2 ± 0.6 |
| C16 | 5.2 ± 1.2 | 7.2 ± 1.9 | 15.8 ± 6.2 | 9.7 ± 2.4 |
| C16:1 | 16.0 ± 3.3 | 21.1 ± 4.5 | 34.8 ± 5.5 | 26.6 ± 2.3 |
| C18 | 4.1 ± 0.9 | 5.3 ± 1.1 | 12.0* ± 2.2 | 8.1 ± 0.8 |
| C18:1 | 29.4 ± 7.0 | 36.6 ± 8.0 | 41.7** ± 3.3 | 27.8 ± 4.4 |
| C20 | 11.0 ± 2.6 | 12.5 ± 2.6 | 17.5 ± 2.6 | 10.1 ± 1.8 |
| C20:1 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.2 ± 0.2 |
| C22 | 12.4 ± 2.7 | 16.8 ± 2.0 | 23.3* ± 2.5 | 13.7^ ± 2.4 |
| C22:1 | 7.6 ± 1.8 | 7.6 ± 1.1 | 12.5 ± 1.1 | 7.5 ± 1.4 |
| C24 | 6.8 ± 1.6 | 10.0 ± 0.9 | 13.5* ± 1.9 | 8.8 ± 1.3 |
| C24:1 | 11.9 ± 3.1 | 17.1 ± 2.5 | 18.5 ± 2.7 | 14.6 ± 2.5 |
| C26 | 0.1 ± 0.0 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.2 ± 0.1 |
| C26:1 | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.1 |
Data are means ± SEM; n = 5 for all groups.