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. 2017 Nov 10;32(3):1222–1235. doi: 10.1096/fj.201700477R

Figure 3.

Figure 3.

CQ treatment increases PI3K inhibitor–induced mitochondrial membrane depolarization. Cells were treated ± 1 μM GDC-0941 or 50 μM CQ. After 24 h of drug treatment, mitochondrial membrane potential was measured by JC-1 staining and flow cytometry. *P < 0.05 by Bonferroni multiple comparison–adjusted post hoc test compared with control unless otherwise indicated with brackets (between GDC and GDC+CQ, or between CQ and GDC+CQ).