Figure 4.

Human immune cell populations in peripheral blood and tumors of the NSCLC (LG1306) and TNBC (MDA-MB-231) Onco-HuNSG model. Whole blood from LG1306 (A) or MDA-MB-231 (B) Onco-HuNSG mice was processed into single-cell suspensions and stained, as described in Materials and Methods, for flow cytometric analysis. Tumor tissues from LG1306 (C) or MDA-MB-231 (D) Onco-HuNSG mice were processed into single-cell suspensions and stained, as described in Materials and Methods, for flow cytometric analysis. The percentage of hCD3⁺CD4⁺ T cells, hCD3⁺CD8⁺ T cells, and hCD19⁺ B cells is shown within CD45⁺ cells. *P < 0.05; **P < 0.01.