Table 1.
Details of studies contributing data to IPD meta-analysis
PI | Setting | N | Events | Dates | Inclusion | Primary outcome | |
Studies with data available | |||||||
EQUIPP30 31 | Professor AS | 5 UK centres | 452 | 14 | 2010–2012 | 22–35 weeks with symptoms of preterm labour | Delivery <34 weeks gestation |
EUFIS*32 | Professor BM | 10 European hospitals | 452 | 48 | 2012–2014 | 24–34 weeks with preterm contractions and intact membranes | Delivery within 7 days of test |
APOSTEL I*33 | van Baaren | 10 Dutch hospitals | 528 | 70 | 2009–2012 | 24–34 weeks with preterm contractions and intact membranes | Days to delivery truncated at 7 days |
QFCAPS (unpublished) |
Dr AK | London teaching hospital | 86 | 2 | 2012–2014 | 24–34 weeks with symptoms of preterm labour Singletons only |
Delivery within 7 days of test |
UCLH/Whit (unpublished) |
Dr ALD | 2 UK centres | 262 | 5 | 2009–2010 | 22–35 weeks with symptoms of preterm labour | Delivery within 7 days of test |
Total | 5 studies | 1783 | 139 | ||||
Studies where data may be available in future | |||||||
STOP study (https://clinicaltrials.gov/ct2/show/NCT01868308) |
Professor M Elovitz | USA teaching hospital | 700 | NK | 2011–2015 | 22–34 weeks Symptomatic women with singleton pregnancy | Delivery before 37 weeks |
*Study unpublished at time of search in April 2014; manuscript now published.
APOSTEL 1, Alleviation of Pregnancy Outcome by Suspending of Tocolysis in Early Labour; EQUIPP, Evaluation of Fetal Fibronectin with a novel bedside Quantitative Instrument for the Prediction of Preterm birth; EUFIS, European Fibronectin Study; IPD, individual participant data; NK, not known; PI, principal investigator; QFCAPS, Quantitative fetalfibronectin, Cervical length and ActimPartus for the prediction of Preterm birth in Symptomatic women; STOP, Screening to Obviate Preterm Birth; UCLH/WHIT, Univesity College London Hospital/Whittington Hospital Study.