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. 2018 Apr 7;8(4):e020656. doi: 10.1136/bmjopen-2017-020656

Table 2.

Mean values of adjusted lung function measurements across quintiles of vitamin A, carotene and vitamin C intake

Q1 Q2 Q3 Q4 Q5 Difference between Q5 and Q1 (95% CI) P values for trend
Vitamin A
 Mean intake (μg RE) 151.2 353.6 573.1 893.9 2140.8
 FEV1 (mL) 2379 2389 2410 2397 2409 30 (10 to 50) 0.008
 FVC (mL) 3119 3136 3158 3148 3152 33 (10 to 57) 0.007
 Predicted FEV1 (%) 91.37 91.44 91.91 91.45 91.94 0.57 (-0.08 to 1.22) 0.185
 Predicted FVC (%) 90.93 91.06 91.45 91.22 91.48 0.55 (0.00 to 1.10) 0.195
Carotene
 Mean intake (μg) 691.1 1747.4 2938.9 4736.1 11 574.1
 FEV1 (mL) 2347 2363 2376 2370 2379 32 (12 to 52) 0.010
 FVC (mL) 3088 3117 3127 3119 3124 36 (13.59) 0.005
 Predicted FEV1 (%) 91.55 92.03 92.26 91.85 92.31 0.76 (0.12 to 1.39) 0.096
 Predicted FVC (%) 91.02 91.68 91.78 91.41 91.82 0.80 (0.26 to 1.33) 0.015
Vitamin C
 Mean intake (mg) 24.2 53.6 84.2 128.8 268.9
 FEV1 (mL) 2411 2423 2436 2441 2453 36 (16.56) <0.001
 FVC (mL) 3117 3122 3132 3140 3154 35 (12.58) 0.014
 Predicted FEV1 (%) 91.3 91.5 91.9 91.99 92.21 0.91 (0.27 to 1.55) 0.050
 Predicted FVC (%) 91.29 91.33 91.58 91.77 92.0 0.71 (0.17 to 1.26) 0.118

Data were adjusted for age, sex, body mass index, energy intake, number of comorbid diseases, alcohol consumption, place of residence smoking history, pack-years (smoking amount), household income and education level. P values were determined using tests for linear trends across increasing quintiles (means) of antioxidant vitamin intake.

FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s; RE, retinol equivalent; Q1, lowest quintile; Q5, highest quintile.