Figure 3.
Percentage of patients achieving remission by conversion to ACPA seronegative status. Antibody titres were determined by ELISA at baseline and months 6 and 12. Baseline to month 6 and baseline to month 12 were carried out as separate analyses. ACPA, anti-citrullinated protein antibody; CDAI, Clinical Disease Activity Index; CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; diff, difference; MTX, methotrexate.