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. 2018 Apr 10;13(4):e0193790. doi: 10.1371/journal.pone.0193790

Table 1. Top 10 transcripts with increased ribosome density and their function (see also S2 Table).

Upregulated transcripts
Name Full name Function FDR 2Log FC
Atf4 Activating transcription factor 4 Transcription factor; apoptosis 1.09E-36 1.96
Scoc Short coiled-coil protein Autophagy 7.83E-11 1.46
Ibtk Inhibitor of Bruton tyrosine kinase Downregulates BTK kinase activity; apoptosis 1.80E-10 1.04
Pnrc2 Proline Rich Nuclear Receptor Coactivator 2 Nonsense-mediated mRNA decay 2.14E-08 1.04
Ddit3 DNA Damage Inducible Transcript 3 Transcription factor; apoptosis 2.30E-08 1.55
Ppp1r15a Protein Phosphatase 1 Regulatory Subunit 15A PPase1 subunit, involved in dephosphorylation of eIF2 4.93E-08 0.92
Ost4 Oligosaccharyltransferase Complex Subunit 4 Post-translational modification 8.12E-08 0.79
Usmg5 Up-Regulated During Skeletal Muscle Growth 5 Homolog Mitochondrial Role 1.18E-07 1.51
Gtf2h5 General Transcription Factor IIH Subunit 5 DNA repair Process 1.64E-07 0.61
Dpm2 Dolichyl-Phosphate Mannosyltransferase Subunit 2 Post-translational modification 2.09E-07 0.80