Figure 3.
Development of porcine primordial follicles in xenografts. Ovarian cortical strips containing primordial follicles were cultured for 7 days before xenografting to SCID mice. After 2 months, the grafts were fixed and stained with H&E. In the grafts of fresh ovarian tissues (a) or vehicle‐treated strips (b), none of the follicles developed beyond the primordial stage. In the grafts treated with 10−6 m testosterone, the follicles developed to the secondary (c) and antral stages which contained growing oocytes (d, e). “r” indicates the renal tissue of SCID mice. The scale bars represent 100 µm