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Cross-reactivity of NP418–426 specific CD8 T cells. PMBC samples of HLA-B*35:01-positive donors were stimulated with 10 MOI LAIV 5:3 (Blue circle) or 10 MOI LAIV 6:2 (Red triangle) for 10 days. The expression of cytokines were estimated by ICS assay after 6 hours of in vitro cultures re-stimulation with Len/17 or HK NP44–52 peptide loaded C1R cells.
