Table 2.
Antigen | Gardasil vaccinated CD4/CD154/IL-2 positive T cells Median frequency (IQR) | Number of subjects | p-value | Cervarix vaccinated CD4/CD154/IL-2 positive T cells Median frequency (IQR) | Number of subjects | p-value |
---|---|---|---|---|---|---|
HPV6 L1 | ||||||
Baseline | 0.000 (0.000–0.003) | 14 | 0.000 (0.000–0.015) | 13 | ||
7 months | 0.080 (0.045–0.130) | 13 | 0.003 | 0.030 (0.010–0.090) | 15 | 0.028 |
12 months | 0.060 (0.040–0.090) | 15 | 0.001 | 0.040 (0.010–0.070) | 15 | 0.021 |
HPV11 L1 | ||||||
Baseline | 0.000 (0.000–0.010) | 14 | 0.000 (0.000–0.005) | 13 | ||
7 months | 0.060 (0.030–0.120) | 15 | 0.001 | 0.020 (0.010–0.110) | 15 | 0.009 |
12 months | 0.050 (0.010–0.090) | 15 | 0.004 | 0.020 (0.008–0.070) | 14 | 0.007 |
HPV16 L1 | ||||||
Baseline | 0.005 (0.000–0.030) | 14 | 0.010 (0.000–0.020) | 15 | ||
7 months | 0.040 (0.020–0.100) | 15 | 0.004 | 0.050 (0.010–0.113) | 14 | 0.003 |
12 months | 0.050 (0.020–0.070) | 15 | 0.018 | 0.030 (0.010–0.050) | 15 | 0.008 |
HPV18 L1 | ||||||
Baseline | 0.000 (0.000–0.003) | 0.000 (0.000–0.005) | 14 | |||
7 months | 0.030 (0.010–0.040) | 15 | 0.016 | 0.040 (0.010–0.070) | 15 | 0.003 |
12 months | 0.020 (0.010–0.050) | 15 | 0.016 | 0.020 (0.000–0.060) | 15 | 0.108 |
HPV31 L1 | ||||||
Baseline | 0.000 (0.000–0.010) | 14 | 0.000 (0.000–0.020) | 15 | ||
7 months | 0.020 (0.010–0.080) | 15 | 0.013 | 0.030 (0.010–0.100) | 15 | 0.006 |
12 months | 0.030 (0.000–0.050) | 15 | 0.028 | 0.030 (0.015–0.075) | 13 | 0.018 |
HPV45 L1 | ||||||
Baseline | 0.000 (0.000–0.020) | 14 | 0.000 (0.000–0.033) | 14 | ||
7 months | 0.020 (0.015–0.035) | 13 | 0.026 | 0.030 (0.000–0.053) | 14 | 0.325 |
12 months | 0.020 (0.010–0.050) | 15 | 0.011 | 0.010 (0.000–0.030) | 13 | 0.929 |