Table 3. Correlation between TK1 values and CTCs or ctDNA mutations.

	TK1 T0 low	TK1 T0 high	Total	p-value
CTCs count				0.014**
CTC negative, n (%)	14 (66.7)	7 (33.3)	21 (72.4)
CTC positive, n (%)	1 (12.5)	7 (87.5)	8 (27.6)
Total, n (%)	15 (51.7)	14 (48.3)	29
PIK3CA or ESR1 mutational status				1**
Wild type, n (%)	10 (47.6)	11 (52.4)	21 (70.0)
Mutant, n (%)	5 (55.6)	4 (44.4)	9 (30.0)
Total, n (%)	15 (50.0)	15 (50.0)	30

Note: CTC negative if CTCs<5 CTCs/7.5 ml of blood, CTC positive if CTCs≥ 5 CTCs/7.5 ml of blood.

**Fisher exact test