Figure 3. Sensitivity to diverse NAMPT inhibitors, FK866, CHS-828, GNE-617, and STF-118804, in HCT116R^FK866 and parental HCT116 cells.

Colony formation by HCT116R^FK866 and parental HCT116 cells after 10 days of treatment with (A) FK866, (B) CHS-828, (C) GNE-617, and (D) STF-118804. Results are averages of two independent experiments, with error bars showing ± SE of triplicates. (E) Drug sensitivities of HCT116R^FK866 and HCT116 in the colony formation assay. HCT116R^FK866 and HCT116 cells were treated with 100 nM each of FK866, CHS-828, GNE-617, STF-118804, and incubated for 10 days. (F) Colony formation (%) are averages of two independent experiments, with error bars showing ± SE of triplicates.