Table 3. Summary of pancreatic juice proteomic biomarkers proposed for the management of pancreatic cancer.
Single biomarker or panel | Utility | Expression patterna | Impact in prognosis | Year | Ref. |
---|---|---|---|---|---|
AMYP, PRSS1, GP2-1, CCDC132, REG-1-Alpha, REG-1-Beta, REG-3-Alpha, and LIPRP2 | Diagnostic | ↑, ↑, ↑, ↑, ↑, ↑, ↑, and ↓ | - | 2014 | [105] |
Mucins and S100A8 or S100A9 | Prognostic | All ↑ | Negative | 2014 | [106] |
MUC-1 | Diagnostic | ↑ | - | 2015 | [107] |
CPA5, LIPRP1, KLK1, HBD, and TTR | Diagnostic | ↓, ↓, ↓, ↑, and ↑ | - | 2015 | [108] |
a Expression pattern observed in pancreatic cancer patients. ↑: upregulated. ↓ downregulated.