Skip to main content

View full-text article in PMC

. 2018 Mar 18;20(2):244–249. doi: 10.22074/cellj.2018.4860

Table 1.

Effect of melatonin on cumulus expansion and nuclear maturation in mouse oocytes


Group	Number of COCs	MI n (mean ± SD)	Cumulus expansionn (mean ± SD)	MIIn (mean ± SD)

Control	198	70 (35.35 ± 2.62)^a,b	165 (83.33 ± 6.39)^d	128 (64.65 ± 4.87)^{f, g}
DMSO	205	95 (43.34 ± 3.20)	137 (66.83 ± 4.34)	110 (53.66 ± 2.82)
Melatonin 10^-6 M	222	32 (14.41 ± 2.14)^{a, c}	194 (87.39 ± 5.56)^e	190 (85.59 ± 5.96)^{f, h}
Melatonin 10^-9M	193	121 (62.69 ± 3.12)^b,c	81 (41.97 ± 2.07)^{d, e}	72 (37.31 ± 2.00)^{g, h}

Within the same column, values with the same letters were significantly different (P<0.05).

DMSO; Dimethyl sulfoxide, COCs; Cumulus-oocyte complex, MI; Metaphase I, and MII; Metaphase II.