Figure 3. Development of Ab to lung-associated SAg in mice injected with exosomes derived from LTxR with BOS and from stable LTxR.
Ab to lung-associated SAg was quantified in mice that were subcutaneously injected with exosomes from LTxR with BOS and stable LTxR using serum samples collected on days 10, 20 and 30. Ab to Col-V were compared in mice injected with stable LTx exosomes and BOS patients derived exosomes (A). Serum Ab concentrations against Kα1T were measured in mice injected with exosomes isolated from LTxR with BOS, stable LTxR, and adult C57BL/6 mice (B).