Figure 6. Serum inflammatory cytokine levels in that were mice immunized with exosomes derived from LTxR diagnosed with BOS and stable LTxR.
Sera collected on day 30 from mice immunized with exosomes derived from LTxR with BOS shown increased inflammatory cytokines IL-1b, IL-2 (p=0.0016), IFN-γ, TNF-α (p=0.031), IL-4, GM-CSF, IL-6, IL-12, IL-17 and decreased IL-10 (p=0.036) compared with stable LTxR recipients analyzed by Luminex assay.