. Author manuscript; available in PMC: 2019 Apr 1.

Published in final edited form as: J Thromb Haemost. 2018 Mar 13;16(4):670–679. doi: 10.1111/jth.13974

Table 3.

Hazard ratios (95% CIs) of incident VTE by time since AF diagnosis: The Atherosclerosis Risk in Communities Study, 1987-2011

	No AF	Time since AF diagnosis

		≤ 6 months	> 6 months

N	13,081	429	1619
# VTE Events	613	16	52
Person-years	259,659	859	9,900

Hazard ratio (95% CI)
Model 1	1 (REF)	6.23 (3.78-10.26)	1.67 (1.25-2.23)
Model 2	1 (REF)	5.08 (3.08-8.38)	1.42 (1.06-1.90)
Model 3	1 (REF)	5.24 (3.17-8.65)	1.55 (1.15-2.09)

CI, confidence interval; VTE, venous thromboembolism; AF, atrial fibrillation.

Model 1 is adjusted for age, sex and race-field center.

Model 2: Model 1+ income, education, physical activity, smoking, waist circumference, height, systolic blood pressure, anti-hypertensive medication, diabetes, prevalent coronary heart disease, prevalent heart failure, prevalent anticoagulant use and eGFR.

Model 3: Model 2 + time-dependent anticoagulant use.