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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: J Thromb Haemost. 2018 Mar 13;16(4):670–679. doi: 10.1111/jth.13974

Table 5.

Hazard ratios (95% CIs) of incident AF by time since VTE diagnosis: The Atherosclerosis Risk in Communities Study, 1987-2011

No VTE Time since VTE diagnosis

≤ 6 months > 6 months

N 14,516 175 438
# AF Events 2,048 13 49
Person-years 279,785 244 2746
Hazard ratio (95% CI)
 Model 1 1 (REF) 5.14 (2.98-8.88) 1.66 (1.25-2.21)
 Model 2 1 (REF) 4.50 (2.61-7.77) 1.49 (1.12-1.98)
 Model 3 1 (REF) 4.15 (2.40-7.17) 0.99 (0.73-1.34)

CI, confidence interval; AF, atrial fibrillation; VTE, venous thromboembolism.

Model 1 is adjusted for age, sex and race-field center.

Model 2: Model 1+ income, education, physical activity, smoking, waist circumference, height, systolic blood pressure, anti-hypertensive medication, diabetes, prevalent coronary heart disease, prevalent heart failure, prevalent anticoagulant use and eGFR.

Model 3: Model 2 + time-dependent anticoagulant use.

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