Table 1.
Women Aged <50 Years | Women Aged ≥50 Years | |||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
TNBC Cases n=252 |
Controls n=2,223 |
TNBC Cases n=306 |
Controls n=2,888 |
|||||
n | %1 | n | %1 | n | %1 | n | %1 | |
Study2 | ||||||||
AABCS | 21 | 8 | 947 | 43 | 44 | 14 | 949 | 33 |
NC-BCFR | 201 | 80 | 323 | 15 | 229 | 75 | 303 | 10 |
SFBCS | 30 | 12 | 953 | 43 | 33 | 11 | 1,636 | 57 |
Time period3 | ||||||||
1995–1999 | 62 | 25 | 1,182 | 53 | 27 | 9 | 1,696 | 59 |
2000–2004 | 77 | 31 | 903 | 41 | 101 | 33 | 1,005 | 35 |
2005–2009 | 113 | 45 | 138 | 6 | 178 | 58 | 187 | 6 |
Race/ethnicity | ||||||||
African American | 38 | 15 | 227 | 10 | 64 | 21 | 414 | 14 |
Asian American | 54 | 21 | 1,007 | 45 | 84 | 27 | 982 | 34 |
Hispanic | 85 | 34 | 611 | 27 | 69 | 23 | 887 | 31 |
Non-Hispanic white | 75 | 30 | 378 | 17 | 89 | 29 | 605 | 21 |
Age (years) | ||||||||
<40 | 97 | 38 | 597 | 27 | 0 | 0 | 0 | 0 |
40–49 | 155 | 62 | 1,626 | 73 | 0 | 0 | 0 | 0 |
50–59 | 0 | 0 | 0 | 0 | 213 | 70 | 1,518 | 53 |
60–75 | 0 | 0 | 0 | 0 | 93 | 30 | 1,370 | 47 |
Education | ||||||||
Some high school or less | 29 | 12 | 369 | 17 | 41 | 13 | 738 | 26 |
High school degree | 29 | 12 | 284 | 13 | 47 | 15 | 517 | 18 |
Technical/vocational school or some college | 81 | 32 | 581 | 26 | 104 | 34 | 724 | 25 |
College or higher degree | 113 | 45 | 989 | 44 | 114 | 37 | 909 | 31 |
Country of birth | ||||||||
U.S.-born | 157 | 62 | 1,006 | 45 | 198 | 65 | 1,553 | 54 |
Foreign-born | 95 | 38 | 1,217 | 55 | 108 | 35 | 1,335 | 46 |
Family history of breast cancer in first-degree relatives | ||||||||
No | 195 | 77 | 2,032 | 92 | 238 | 78 | 2,538 | 89 |
Yes | 57 | 23 | 182 | 8 | 67 | 22 | 327 | 11 |
Unknown4 | 0 | 0 | 9 | 0 | 1 | 0 | 22 | 1 |
Personal history of benign breast disease | ||||||||
No | 227 | 90 | 1,866 | 84 | 241 | 79 | 2,175 | 75 |
Yes | 25 | 10 | 357 | 16 | 65 | 21 | 709 | 25 |
Unknown4 | 0 | 0 | 0 | 4 | ||||
Alcohol consumption in reference year (drinks/week) | ||||||||
0 | 171 | 68 | 1,396 | 63 | 205 | 67 | 1,939 | 67 |
≤2.0 | 18 | 7 | 346 | 16 | 22 | 7 | 405 | 14 |
>2.0 | 62 | 25 | 481 | 22 | 77 | 25 | 542 | 19 |
Unknown4 | 1 | 0 | 2 | 2 | ||||
Height (cm, quartiles)5 | ||||||||
<154.9 | 25 | 10 | 472 | 21 | 45 | 15 | 842 | 29 |
155.0–159.9 | 52 | 21 | 742 | 33 | 86 | 28 | 929 | 32 |
160.0–165.0 | 90 | 36 | 502 | 23 | 78 | 26 | 621 | 22 |
>165.0 | 83 | 33 | 504 | 23 | 95 | 31 | 487 | 17 |
Unknown4 | 2 | 3 | 2 | 9 | ||||
Body mass index (kg/m2) in reference year | ||||||||
<25 | 128 | 51 | 1,303 | 59 | 125 | 41 | 1,244 | 43 |
25–29.9 | 68 | 27 | 505 | 23 | 79 | 26 | 877 | 31 |
≥30 | 53 | 21 | 411 | 19 | 100 | 33 | 754 | 26 |
Unknown4 | 3 | 4 | 2 | 13 | ||||
Oral contraceptive use | ||||||||
Never | 54 | 21 | 712 | 32 | 85 | 28 | 1,361 | 48 |
Former | 158 | 63 | 1,378 | 62 | 218 | 71 | 1,497 | 52 |
Current | 40 | 16 | 126 | 6 | 3 | 1 | 7 | 0 |
Unknown4 | 7 | 23 | ||||||
Menopausal status in reference year | ||||||||
Premenopausal | 209 | 87 | 1,881 | 90 | 41 | 14 | 270 | 10 |
Postmenopausal | 32 | 13 | 211 | 10 | 256 | 86 | 2,467 | 90 |
Unknown4 | 11 | 131 | 11 | 151 | ||||
Hormone therapy use (postmenopausal women) | ||||||||
Never | 25 | 78 | 107 | 51 | 137 | 54 | 1,181 | 48 |
Former | 3 | 9 | 49 | 23 | 79 | 31 | 739 | 30 |
Current | 4 | 13 | 53 | 25 | 36 | 14 | 528 | 22 |
Unknown4 | 0 | 2 | 4 | 19 |
Percentages may not add up to 100 due to rounding.
AABCS: Los Angeles County Asian Breast Cancer Study; NC-BCFR: Northern California site of the Breast Cancer Family Registry; SFBCS: San Francisco Bay Area Breast Cancer Study.
Year of diagnosis for cases, year of selection or interview for controls.
Not included in percentages.
Quartiles among all controls.